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Wellbutrin sr generico, bupropion, venlafaxine, escitalopram, and aripiprazole.
This systematic review and meta-analysis was conducted by means of meta-analysis. The Cochrane Collaboration's tool for assessing the risk of bias in systematic reviews (the I2 statistic) was used to assess risk of bias, and the following criteria for assessing systematic review were applied. First, it was assumed that the reviewers were blinded to inclusion and exclusion criteria. Second, the methods were coded for completeness. Third, the full text of articles were obtained, and the systematic review report was then published. A total of 1,633 full papers with an average of 4.2 citations (range 1–23) were identified. Two authors (N.B.-A. and S.M.B.) independently abstracted data from all included studies in accordance with the Preferred Reporting Items for Systematic Reviews (PRISMA) statement (16).
Results
Inclusion criteria and baseline characteristics of study populations
Two hundred and thirty-six studies were included in the main analysis. studies were published from 1966 through March 2016. The median number of patients was 13.8; median duration of treatment was 6.5 months; median duration of follow-up ranged from 8 to 24 months. Nine of the excluded studies were on same population as the included studies, and all of them had small numbers.
The median age of included studies were: 12 years (range 4–38 years); mean follow-up was 6.9 months (range 6–15 months). The mean duration of bupropion use was 13.5 months (range 7–21 months), the mean duration of escitalopram use was 16.2 months (range 12–33 months), and the mean duration of venlafaxine use was 28.0 months (range 24–42 months).
The median number of doses medication was: Is meloxicam an over the counter drug 4 for bupropion and 16 escitalopram (range 12–32); 14 for venlafaxine and 9 aripiprazole (range 14–22); 11 for bupropion and 12 paroxetine (range 10–19). The median dose of bupropion used ranged from 20 mg to 160 mg/day or 40 mg to 320 mg/day, the mean range for aripiprazole was 5–13.4 mg/day and the mean for paroxetine was 0.3–6.4 mg/day (17).
The median duration of initial medication was: 12 hours for bupropion and 19 escitalopram; 2-5 days for venlafaxine, paroxetine and aripiprazole; 6–13 days for bupropion, venlafaxine, paroxetine, and aripiprazole.
The median initial dose of medication in the included studies ranged from 30 mg to 800 and from 12 32.5 mg; the mean of all dose were 27 mg (16) and 28.4 (20).
The median duration of medication used was: 6 months for bupropion 10 mg, 8–10 months for escitalopram 400 mg, 12–16 months on aripiprazole 200 mg, and 14–16 months for venlafaxine 300 mg (17).
Bupropion and escitalopram
The mean baseline for bupropion use was 5.2 (range 2–13) and for escitalopram generic pharmacy xanax use 2.6 years (range 1–6). In the studies included systematic review and meta-analysis of bupropion, there were statistically significant differences in mean baseline bupropion use between the two groups (pooled, 5.1 vs 2.8 mg/day; I = 0.40 for bupropion vs 0.23 escitalopram). The mean baseline for venlafaxine use was 3.8 (range 0.4–10) and for aripiprazole 1.9 (range 1–9).
Bupropion and escitalopram were found to be well tolerated in all studies and no serious adverse effects on clinical efficacy were reported after a median total duration of 6 months for bupropion (range 5–24 months) and escitalopram 10–24 months). No significant associations were shown between dosage or length of use and adverse effects.
Bupropion and venlafaxine
The mean baseline for bupropion use was 5.2 (range 3.0–13.2) and for venlafaxine use 2.8 years (range 1–6.35) (Table 1). In the studies included systematic review and meta-analysis of bupropion venl.
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